Dr Mendelson is known for his contributions on the surgical anatomy of the face. His several important anatomical findings are published in a series of classic papers, on the Surgical Anatomy of the Temple, the retaining ligaments of the orbit and Prezygomatic Space, the Surgical Anatomy of the Mid Cheek as well as the Surgical Anatomy of the Premasseter space and the Jowl. The terms Prezygomatic space and Premasseter spaces were introduced as well as the important surgical concept of Facial Spaces, which is now beginning to be appreciated by plastic surgeons.
Dr Mendelson is one of the founding members and Head of the Faculty of the Melbourne Advanced Facial Anatomy Course (MAFAC). This renowned and intensive cadaver dissection teaching course, prepares surgeons to advance their understanding of facial anatomy to the level where they can comfortably and safely incorporate the benefits of recent advances into their clinical practice. The Course has been conducted on twenty three occasions in both Melbourne, Australia and at the American Society of Aesthetic Plastic Surgery Meetings in New Orleans (2019), New York (2018), San Diego (2017), Las Vegas (2016), Quebec (2015), San Francisco (2014).